Physician Assistant Locum Tenens Jobs in South Carolina

Physician Assistant (PA) - Cardiology - General/Other in Greenwood, SC - This Cardiology APP position is primarily outpatient, offering a Monday-Friday schedule with minimal inpatient coverage. Work alongside a collaborative team of experienced cardiologists and APPs in a supportive environment that welcomes both new graduates and experienced providers transitioning into cardiology. The role focuses on follow-up appointments, consultations, routine visits, and acute sick visits, with strong mentorship and opportunities for professional growth. This opportunity includes a $15,000 sign-on bonus, loan repayment, comprehensive benefits, paid time off, and productivity incentives after the first year. Located in a welcoming community with easy access to larger metropolitan areas, you'll enjoy an excellent quality of life, affordable living, outdoor recreation, and the chance to build a rewarding long-term career with a growing cardiovascular team. For more information on this and our other opportunities nationwide, call 954-837-2779, ask for Sarah Jeske, and email your most up-to-date CV to Please reference JOB-3345370 * Full Time Permanent Position * New grads with relevant experience welcome to apply * Mostly clinic work * General Cardiology * 15k sign-on bonus * Loan repayment * Interviewing and hiring immediately * JOB-3345370 * Our services are free for you * We help negotiate your salary and contract * We coordinate interviews and help with licenses * Specialized recruiters match your career preferences * Experienced support teams take care of every detail

Physician Assistant (PA) - Family Practice in Laurens, SC - We are seeking a dedicated and experienced Nurse Practitioner or Physician Assistant to join our Family Medicine team as a floating provider. This role will support patient care across multiple outpatient family medicine sites in Abbeville, Greenwood, Laurens, McCormick, and Saluda counties in South Carolina. The ideal candidate will be passionate about patient-centered care, preventive health, and chronic disease management, while building strong, trusting relationships with patients and their families. Key Responsibilities: * Provide comprehensive primary care services to patients across the lifespan. * Travel regularly to assigned family medicine sites within the designated counties: Abbeville, Greenwood, Laurens, McCormick, and Saluda, SC * Deliver high-quality, evidence-based care with an emphasis on wellness, prevention, and chronic condition management. * Collaborate effectively with physicians, nurses, and other team members to coordinate patient care. * Educate patients and families about treatment plans, medications, and health maintenance. * Document patient encounters accurately and timely in the electronic health record system. Compensation & Benefits: * Starting Salary: $100,000 * Medical, dental, and vision insurance * Paid time off and holidays * Retirement plan options * Continuing education support * Mileage reimbursement for travel between sites Requirements: * Graduate of an accredited Advanced Practice Registered Nurse/Nurse Practitioner program or Physician Assistant program. * Minimum of 2 years of experience in a primary care or family medicine setting required. * Active and unrestricted South Carolina medical license. * Certified or eligible for certification in area of specialty (FNP, PA-C). Join a mission-driven team that values collaboration, compassion, and community health. If you are a motivated and adaptable provider looking to make a meaningful impact across several South Carolina communities, we encourage you to apply.

Physician Assistant (PA) - Family Practice in Abbeville, SC - We are seeking a dedicated and experienced Nurse Practitioner or Physician Assistant to join our Family Medicine team as a floating provider. This role will support patient care across multiple outpatient family medicine sites in Abbeville, Greenwood, Laurens, McCormick, and Saluda counties in South Carolina. The ideal candidate will be passionate about patient-centered care, preventive health, and chronic disease management, while building strong, trusting relationships with patients and their families. Key Responsibilities: * Provide comprehensive primary care services to patients across the lifespan. * Travel regularly to assigned family medicine sites within the designated counties: Abbeville, Greenwood, Laurens, McCormick, and Saluda, SC * Deliver high-quality, evidence-based care with an emphasis on wellness, prevention, and chronic condition management. * Collaborate effectively with physicians, nurses, and other team members to coordinate patient care. * Educate patients and families about treatment plans, medications, and health maintenance. * Document patient encounters accurately and timely in the electronic health record system. Compensation & Benefits: * Starting Salary: $100,000 * Medical, dental, and vision insurance * Paid time off and holidays * Retirement plan options * Continuing education support * Mileage reimbursement for travel between sites Requirements: * Graduate of an accredited Advanced Practice Registered Nurse/Nurse Practitioner program or Physician Assistant program. * Minimum of 2 years of experience in a primary care or family medicine setting required. * Active and unrestricted South Carolina medical license. * Certified or eligible for certification in area of specialty (FNP, PA-C). Join a mission-driven team that values collaboration, compassion, and community health. If you are a motivated and adaptable provider looking to make a meaningful impact across several South Carolina communities, we encourage you to apply.

Locum Physician Assistant (PA) - Pathology in South Carolina - We are seeking a  Board-Certified/ASCP Pathology Physician Assistant to provide full-time locum coverage. This is an excellent opportunity to work in a supportive environment with predictable hours and a manageable caseload. 📅 ASSIGNMENT DETAILS * Start Date: February 12, 2026 * End Date: Open until FTE is hired * Schedule: Monday–Friday, 8:00 AM – 5:00 PM (30–60 min unpaid lunch) * On Call: None * Shift Type: Complete daily caseload prior to end of shift; OT applies if necessary 🏥 PRACTICE ENVIRONMENT * Average 30 cases per day * Work alongside 2 pathologists and 1 clinical lab assistant * Credentialing handled through onboarding and Employee Health (not MSO) * Must be able to perform grossing ✅ REQUIREMENTS * ASCP certified (required) * Experience in pathology laboratory procedures * Ability to manage daily caseload efficiently * Flexible and reliable team player 📍 Location Perks Enjoy a scenic coastal setting with mild weather, great community amenities, and a relaxed lifestyle while practicing in a well-supported pathology department. 📩 Interested? Reach out to review rates, scheduling, and next steps.

Physician Assistant (PA) - Surgery - Vascular in South Carolina - A locally owned, not-for-profit hospital system is seeking a Physician Assistant (PA) to join their expanding vascular surgery team just 70 miles from Myrtle Beach, South Carolina. This is an excellent opportunity to work in a 100% inpatient, hospital-based setting, assisting in the OR and providing care for vascular surgery patients. Position Details * Schedule: Monday-Friday, 7:30 AM - 4:30 PM * New graduates are welcome to apply! * Responsibilities include assisting in surgeries and rounding on patients. Compensation & Benefits * Salaried position based on experience * Hospital-employed position * Medical, dental, and vision insurance * 401K * $2,500 CME allowance + 5 CME days * Liability insurance coverage * Time off: 25 PTO days annually * Sign-on bonus * Relocation assistance Community Details Nestled in the heart of the Pee Dee region, is a city that offers the perfect blend of Southern charm, modern convenience, and natural beauty. With its vibrant downtown brimming with locally owned boutiques, trendy cafes, and art galleries, this community provides a warm and welcoming atmosphere for residents and visitors alike. Enjoy a slower pace of life while being just a stone's throw from scenic parks, historic landmarks, and exciting festivals. Whether you're savoring the rich flavors of the local food scene or exploring the area's rich history, this is a hidden gem where community spirit and endless opportunities for adventure await. Join a dedicated team in a vibrant and supportive community near South Carolina's beautiful coastline. Apply today to advance your career with a trusted healthcare system! TLM-2412-99795

Physician Assistant (PA) - Family Practice in South Carolina - A Physician Assistant is sought to deliver comprehensive outpatient care for patients of all ages in a Primary Care Clinic. The PA will focus on preventive health, chronic disease management, and acute care services, while coordinating care with specialists as needed. This position offers a balanced schedule, a supportive environment, and excellent benefits. Position Overview * Outpatient-only clinical role (no inpatient responsibilities) * Standard office hours: * Monday-Thursday: 8:00 AM-5:00 PM * Friday 8:00 AM-12:00 PM * Protected administrative time: 4.5 days clinic / 0.5 day admin per week * 36 patient contact hours / 4 administrative hours * Minimal call shared on a 1:7-1:8 rotation * Cerner EMR * Dedicated support: a personal nurse and access to medical assistants Patient Volume & Population * Average daily volume: 18-22 patients * Patient census: Primarily adult and geriatric, with some pediatrics * Mixed rural/suburban population * Common conditions: hypertension, diabetes, chronic disease follow-up, acute issues, wellness exams Visit Types & Procedures * Sick visits, chronic disease follow-ups, annual physicals, acute care * In-office procedures may include: * Minor dermatologic procedures * Joint injections * Skin biopsies * Routine vaccinations * Women's health screenings Compensation & Benefits * $5,000 sign-on bonus * Guaranteed salary based on experience * Comprehensive health, dental, and vision coverage * Supplemental options: short/long-term disability, accidental, cancer, and life insurance * Retirement plans with an employer match * Student Loan Repayment: PSLF-eligible * CME: 5 days + $2,000 annually * Malpractice & tail coverage provided * 24 days PTO and flexible scheduling for strong work-life balance Requirements * NCCPA Certified * New and experienced providers are encouraged to apply About the Area Located in beautiful coastal South Carolina, the region offers an exceptional quality of life: * Cost of living below the national average * Excellent public and private schools * Home to Coastal Carolina University * 215+ sunny days each year with an average temperature of 74° * Proximity to the beaches of Myrtle Beach * Entertainment options include amusement parks, live shows, nightlife, and shopping * Outdoor activities: kayaking, hiking, fishing, and golfing * Diverse dining from seafood to Southern cuisine and international options Apply today to find out more! TLM-2512-101657

Physician Assistant (PA) - Surgery - Plastic in South Carolina - A growing, locally governed healthcare system located on the South Carolina Coast between Savannah and Charleston has an opening for an experienced Plastic Surgery Physician Assistant to provide care in both the clinic and operative setting . This role blends patient-facing care with surgical support, offering a dynamic opportunity to work alongside a collaborative surgical team. Key Responsibilities: * Conduct initial and ongoing patient assessments, including histories and physical exams * Evaluate patients' medical and physical status * Develop and manage individualized treatment plans * Assist in surgical procedures and provide perioperative support * Document care accurately in the medical record * Prescribe and dispense medications in accordance with state regulations and supervisory guidelines Compensation & Benefits: * Salary based on experience * Comprehensive benefits package (medical, dental, vision, retirement) * Paid time off and holidays * Continuing education and professional development support * Leadership development programs and mentorship opportunities * Career advancement pathways within a growing healthcare system * Employee recognition and engagement programs Qualifications: * NCCPA Certification * Minimum of 3 years of experience as a Physician Assistant * Experience in plastic surgery or another surgical specialty About the Organization: This locally governed, community-focused healthcare system is one of the largest in the region between Charleston and Savannah and is experiencing rapid growth, including a new hospital, expanded services, and significant investment in workforce development and employee experience. About the Community: Located in South Carolina's scenic Lowcountry, this coastal area offers a blend of historic charm, waterfront living, and easy access to Charleston and Savannah, making it ideal for those seeking a relaxed lifestyle near vibrant cultural centers. If you are a dedicated Physician Assistant looking to grow your career in a collaborative and innovative surgical environment, we encourage you to apply today . TLM-2606-103109

Physician Assistant (PA) in South Carolina - Seeking a Physician Assistant to join a Cancer Care team near Hilton Head. You will be part of a physician-led community hospital with a close-knit, supportive environment. This opportunity offers both professional satisfaction and a desirable lifestyle in a charming coastal community. Position Highlights * Currently 1 Hem/Onc and 2 Nurse Practitioners (expanding to 4 APPs) * Excellent ancillary support staff - genetic counselors, nutritionists, social workers, etc * Average 15 patients/day * Primarily outpatient * Call 1:3 (phone call consults) * Radiation oncology and infusion center on-site Recruitment Package * Salary $130-140K based on experience * RVU bonus AND quality bonuses (paid quarterly) * Sign-on bonus * Full benefits package: medical, dental, vision, vacation, paid malpractice, CME allowance, time off, retirement plan, paid licensure * State Pension plan About Beaufort, South Carolina This beautiful coastal community is conveniently located 35 miles from Hilton Head, 70 miles from Charleston, and 40 miles from Savannah, GA. Tucked into winding, historic streets framed by natural foliage and centuries-old, moss-draped live oak trees, this town is more than a hidden Lowcountry gem; it's a transformative destination that has charmed visitors since 1512. Breathe in the salt air. Breathe out, transformed. LP-2603-102343

Physician Assistant (PA) - Emergency Medicine in South Carolina - A nationally recognized, state-of-the-art healthcare system in Florence, South Carolina , is adding a full-time BC/BE Emergency Medicine residency-trained physician to their hospital-employed team. Highlights * 80-bed Emergency Department, separate psych holding area * Average of 16 shifts per month * Variety of day and night shifts available * 8-hour, 9-hour, or 12 hour shifts * Excellent earning potential: day shift pay and night/weekend shift pay with an annual productivity bonus * Sign-on bonus and relocation allowance * Comprehensive benefits include health insurance, paid malpractice, CME, retirement plan, and more Community Located in the Pee Dee region, in northeastern South Carolina, is the community of Florence. Home to 40,000 people, this area boasts warm weather, plenty of outdoor recreational opportunities, and a lively arts and entertainment scene. Florence has a revitalized downtown center, great dining, shopping, concerts, art shows, museum, an outdoor market, historical re-enactments and so much more. Centrally located, Florence is only 1 hour and 20 minutes from Columbia, 1 hour and 30 minutes from Myrtle Beach, and a little over 2 hours from Charlotte, Charleston and Wilmington! ES-2606-102967

Physician Assistant (PA) - Occupational Medicine in South Carolina - A well-respected healthcare organization has a new opening for an experienced Physician Assistant to provide comprehensive occupational health and primary care services at an on-site clinic located within a paper manufacturing facility in northeastern South Carolina, near the North Carolina border . This is a hospital-employed position offering a predictable weekday schedule, strong compensation and benefits, and the opportunity to practice with a high level of autonomy while caring for a consistent patient population. Compensation & Benefits * Salaried position based on experience * Hospital-employed role with long-term stability * Medical, dental, and vision insurance * 401(k) retirement plan * $2,500 CME allowance + 5 CME days annually * Professional liability insurance * Generous paid time off (PTO) * Sign-on bonus * Relocation assistance available Position Details * On-site clinic located within a large manufacturing facility * Monday-Friday schedule * 36 hours per week * No call, no nights, no weekends * Patient volume of approximately 6-10 patients per day * Care provided to employees and their dependents is covered under the health plan * This role will serve as the sole provider at the clinic * Medical Assistant support may be added in the future based on patient volume Scope of Practice * Care for employees and their dependents * Occupational health and workers' compensation cases * Injury care and minor procedures (e.g., suturing) * DOT physicals and drug screenings * Sick visits and primary care services Candidate Qualifications * NCCPA Certification * Preferred: 2+ years of clinical experience in occupational medicine, primary care, urgent care, or emergency medicine * Comfortable working independently with minimal on-site support * Proficient in physical exams and minor procedures * DOT certification is not required at hire, but must be obtained after joining. Community: Located in northeastern South Carolina near the North Carolina state line , this small community offers a quiet, close-knit atmosphere with easy access to larger metro areas. It is approximately 90 minutes east of Charlotte, NC, about 90 minutes south of Fayetteville, NC, and roughly two hours from Columbia, SC. Residents enjoy a relaxed, affordable lifestyle while remaining within convenient driving distance of major cities, regional airports, and South Carolina's coastal destinations. Why This Opportunity? This role is ideal for a Physician Assistant seeking weekday-only hours, professional autonomy, and the security of a hospital-employed position-without the demands of nights, weekends, or call. The clinic serves a close-knit workforce and their families, allowing for meaningful continuity of care in a low-volume, high-quality setting. Apply today to find out more! TLM-2604-102540